Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth.

The adult heart relies predominantly on fatty acids (FA) for energy generation, and defects in FA catabolism cause dramatic left ventricular (LV) growth in early age. Since lipoprotein lipase (LPL) is the key enzyme in plasma triglyceride catabolism and is highly expressed in the myocardium, we inve...

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Bibliographic Details
Main Authors: Flavell, D, Wootton, P, Myerson, S, World, M, Pennell, D, Humphries, SE, Talmud, P, Montgomery, H
Format: Journal article
Language:English
Published: 2006