TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed.

Tumour necrosis factor alpha (TNFα) is a potent cytokine that signals through nuclear factor kappa B (NFκB) to activate a subset of human genes. It is usually assumed that this involves RNA polymerases transcribing responsive genes wherever they might be in the nucleus. Using primary human endotheli...

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Bibliographic Details
Main Authors: Papantonis, A, Kohro, T, Baboo, S, Larkin, J, Deng, B, Short, P, Tsutsumi, S, Taylor, S, Kanki, Y, Kobayashi, M, Li, G, Poh, H, Ruan, X, Aburatani, H, Ruan, Y, Kodama, T, Wada, Y, Cook, P
Format: Journal article
Language:English
Published: 2012