Asymmetric synthesis of pyrrolizidines, indolizidines and quinolizidines via a double reductive cyclisation protocol

This account describes an overview of the asymmetric syntheses of pyrrolizidines, indolizidines and quinolizidines via a common double reductive cyclisation protocol. The highly diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester incorporating a terminal...

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Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Roberts, P, Thomson, J
Format: Journal article
Published: Thieme Publishing 2017