Cardiopulmonary phenotype associated with human PHD2 mutation
Oxygen-dependent regulation of the erythropoietin gene is mediated by the hypoxiainducible factor (HIF) family of transcription factors. When oxygen is plentiful, HIF undergoes hydroxylation by a family of oxygen-dependent prolyl hydroxylase domain (PHD) proteins, promoting its association with the...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Wiley
2017
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