The L-enantiomers of D-sugar-mimicking iminosugars are noncompetitive inhibitors of D-glycohydrolase?
1,4-Dideoxy-1,4-imino-l-arabinitol (l-AB1) and 2,5-dideoxy-2,5-imino-l- mannitol (l-DMDP) are much more potent inhibitors of isomaltase than their d-enantiomers. d-Enantiomers inhibited isomaltase in a competitive manner, whereas l-enantiomers were noncompetitive inhibitors of the enzyme. Similarly...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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