Inferring strain mixture within clinical plasmodium falciparum isolates from genomic sequence data

We present a rigorous statistical model that infers the structure of P. falciparum mixtures-including the number of strains present, their proportion within the samples, and the amount of unexplained mixture-using whole genome sequence (WGS) data. Applied to simulation data, artificial laboratory mi...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: O'Brien, J, Iqbal, Z, Wendler, J, Amenga-Etego, L
التنسيق: Journal article
اللغة:English
منشور في: Public Library of Science 2016