Genes encoding the Ti beta subunit of the antigen/MHC receptor undergo rearrangement during intrathymic ontogeny prior to surface T3-Ti expression.
To obtain further information about the ontogeny of the T-cell antigen/MHC receptor, a Ti beta subunit cDNA probe and heteroantisera specific for the Ti alpha and Ti beta subunits were utilized to characterize human T-lineage cells. Analysis of thymic tumors and normal thymocytes at both the DNA and...
Main Authors: | Royer, H, Acuto, O, Fabbi, M, Tizard, R, Ramachandran, K, Smart, J, Reinherz, E |
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Format: | Journal article |
Language: | English |
Published: |
1984
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