TARG1 protects against DNA ADP-ribosylation stress

<p>ADP-ribosylation is a modification that can target a variety of macromolecules and can regulate an array of important cellular processes. ADP-ribosylation is catalysed by ADP-ribosyltransferases that use NAD+ as a cosubstrate to transfer ADP-ribose onto target molecules. The resulting modif...

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Bibliographic Details
Main Author: Tromans-Coia, C
Other Authors: Ahel, I
Format: Thesis
Language:English
Published: 2020