Excessive synchronization of basal ganglia neurons at 20 Hz slows movement in Parkinson's disease.

Excessive synchronization of neuronal activity at around 20 Hz is a common finding in the basal ganglia of patients with untreated Parkinson's disease (PD). Correlative evidence suggests, but does not prove, that this spontaneous activity may contribute to slowness of movement in this condition...

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Bibliographic Details
Main Authors: Chen, C, Litvak, V, Gilbertson, T, Kühn, A, Lu, C, Lee, S, Tsai, C, Tisch, S, Limousin, P, Hariz, M, Brown, P
Format: Journal article
Language:English
Published: 2007