Evidence for the role of megalin in renal uptake of transthyretin.

The kidney is a major organ for uptake of the thyroid hormone thyroxine (T(4)) and its conversion to the active form, triiodothyronine. In the plasma, one of the T(4) carriers is transthyretin (TTR). In the present study we observed that TTR, the transporter of both T(4) and retinol-binding protein,...

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Bibliographic Details
Main Authors: Sousa, M, Norden, A, Jacobsen, C, Willnow, T, Christensen, E, Thakker, R, Verroust, P, Moestrup, S, Saraiva, M
Format: Journal article
Language:English
Published: 2000