The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis.

Ankylosing spondylitis (AS) is a common and highly heritable inflammatory arthropathy. Although the gene HLA-B27 is almost essential for the inheritance of the condition, it alone is not sufficient to explain the pattern of familial recurrence of the disease. We have previously demonstrated suggesti...

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Bibliographic Details
Main Authors: Timms, A, Crane, A, Sims, A, Cordell, H, Bradbury, L, Abbott, A, Coyne, MR, Beynon, O, Herzberg, I, Duff, G, Calin, A, Cardon, L, Wordsworth, B, Brown, M
Format: Journal article
Language:English
Published: 2004