Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.

Neural stem cells (NSCs) in the adult rat subventricular zone (SVZ) generate new striatal neurons during several months after ischemic stroke. Whether the microglial response associated with ischemic injury extends into SVZ and influences neuroblast production is unknown. Here, we demonstrate increa...

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Bibliographic Details
Main Authors: Thored, P, Heldmann, U, Gomes-Leal, W, Gisler, R, Darsalia, V, Taneera, J, Nygren, J, Jacobsen, SE, Ekdahl, C, Kokaia, Z, Lindvall, O
Format: Journal article
Language:English
Published: 2009