Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.

In a previous study, we identified somatic mutations of SF3B1, a gene encoding a core component of RNA splicing machinery, in patients with myelodysplastic syndrome (MDS). Here, we define the clinical significance of these mutations in MDS and myelodysplastic/myeloproliferative neoplasms (MDS/MPN)....

书目详细资料
Main Authors:	Malcovati, L, Papaemmanuil, E, Bowen, D, Boultwood, J, Della Porta, MG, Pascutto, C, Travaglino, E, Groves, M, Godfrey, A, Ambaglio, I, Gallì, A, Vià, D, Conte, S, Tauro, S, Keenan, N, Hyslop, A, Hinton, J, Mudie, L, Wainscoat, J, Futreal, P, Stratton, MR, Campbell, P, Hellström-Lindberg, E, Cazzola, M
格式:	Journal article
语言:	English
出版:	2011

相似书籍

Myelodysplastic/myeloproliferative disorders
由: Luca Malcovati, et al.
出版: (2008-01-01)

Somatic mutations of calreticulin in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms
由: Luca Malcovati, et al.
出版: (2014-11-01)

Risk assessment in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
由: Mario Cazzola
出版: (2011-03-01)

Clinical evaluation of extra-hematologic comorbidity in myelodysplastic syndromes: ready-to-wear versus made-to-measure tool
由: Matteo G. Della Porta, et al.
出版: (2012-04-01)

Deregulated Gene Expression Pathways in Myelodysplastic Syndrome Hematopoietic Stem Cells
由: Pellagatti, A, et al.
出版: (2009)

Clonality in the myelodysplastic syndromes.
由: Boultwood, J, et al.
出版: (2001)

Somatic Mutation of SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts
由: Malcovati, L, et al.
出版: (2011)

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells.
由: Pellagatti, A, et al.
出版: (2010)

Molecular basis of myelodysplastic/myeloproliferative neoplasms
由: Andreas Reiter, et al.
出版: (2009-12-01)

Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
由: Pellagatti, A, et al.
出版: (2010)

Molecular pathogenesis of the myelodysplastic syndromes
由: Boultwood, J, et al.
出版: (1999)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome.
由: Pellagatti, A, et al.
出版: (2011)

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
由: Pellagatti, A, et al.
出版: (2011)

Neutrophil PRV-1 gene expression in myeloproliferative, myelodysplastic and reactive blood disorders
由: Zhang, J, et al.
出版: (2004)

Gene Expression Profiling of CD34(+) Cells in Patients with Myelodysplastic Syndromes
由: Pellagatti, A, et al.
出版: (2008)

Risk stratification based on both disease status and extra-hematologic comorbidities in patients with myelodysplastic syndrome
由: Matteo G. Della Porta, et al.
出版: (2011-03-01)

Clinical and biological implications of driver mutations in myelodysplastic syndromes.
由: Papaemmanuil, E, et al.
出版: (2013)

MYELODYSPLASTIC/MYELOPROLIFERATIVE DISEASES
由: I. N. Subortseva, et al.
出版: (2017-01-01)

Telomere length in myelodysplastic syndromes.
由: Boultwood, J, et al.
出版: (1995)

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes.
由: Pellagatti, A, et al.
出版: (2009)

Myelodysplastic syndromes
由: Eva Hellström Lindberg
出版: (2018-06-01)

Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
由: Pellagatti, A, et al.
出版: (2010)

Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
由: Pellagatti, A, et al.
出版: (2010)

Frequent Mutation of the Polycomb-Associated Gene ASXL1 in the Myelodysplastic Syndromes and in Acute Myeloid Leukaemia
由: Boultwood, J, et al.
出版: (2009)

Impact of the degree of anemia on the outcome of patients with myelodysplastic syndrome and its integration into the WHO classification-based Prognostic Scoring System (WPSS)
由: Luca Malcovati, et al.
出版: (2011-10-01)

High Throughput Targeted Gene Sequencing in 738 Myelodysplastic Syndromes Patients Reveals Novel Oncogenic Genes, Rare Driver Mutations and Complex Molecular Signatures with Potential Impact for Patient Diagnosis and Prognosis in the Clinic
由: Papaemmanuil, E, et al.
出版: (2012)

Identification of aberrant splicing events in myelodysplastic syndrome patients with splicing factor gene mutations
由: Pellagatti, A, et al.
出版: (2017)

Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes.
由: Pellagatti, A, et al.
出版: (2013)

Gene expression profiling in the myelodysplastic syndromes.
由: Pellagatti, A, et al.
出版: (2005)

Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1
由: Ilaria Ambaglio, et al.
出版: (2013-03-01)

Genome sequencing in the management of myelodysplastic syndromes and related disorders
由: Mario Cazzola, et al.
出版: (2024-10-01)

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR GENE IN MYELODYSPLASTIC SYNDROMES - REPLY
由: Boultwood, J, et al.
出版: (1991)

COMPREHENSIVE ANALYSIS OF MUTATION STATUS, GENE EXPRESSION PROFILES, BLOOD AND BONE MARROW COUNTS AND OUTCOME IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES
由: Pellagatti, A, et al.
出版: (2014)

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.
由: Boultwood, J, et al.
出版: (2010)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes: differences between early and advanced cases and analysis of apoptosis-related genes
由: Pellagatti, A, et al.
出版: (2007)

Comparison and Implications of Mutational Profiles of Myelodysplastic Syndromes, Myeloproliferative Neoplasms, and Myelodysplastic/Myeloproliferative Neoplasms: A Meta-Analysis
由: Ziqi Wan, et al.
出版: (2020-10-01)

Expression profiling of CD34+cells in patients with myelodysplastic syndromes with and without a del(5q)
由: Pellagatti, A, et al.
出版: (2005)

Genome-wide analysis of copy number change and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density SNP arrays
由: Wang, L, et al.
出版: (2007)

Examining disease boundaries: Genetics of myelodysplastic/myeloproliferative neoplasms
由: Michael J. Hochman, et al.
出版: (2021-08-01)

Myelodysplastic and myeloproliferative diseases in children: current concepts
由: Vyas, P
出版: (2014)