Comparative analysis of the CDR loops of antigen receptors

The adaptive immune system uses two main types of antigen receptors: T-cell receptors (TCRs) and antibodies. While both proteins share a globally similar β-sandwich architecture, TCRs are specialised to recognise peptide antigens in the binding groove of the major histocompatibility complex, while a...

Full description

Bibliographic Details
Main Authors: Wong, W, Leem, J, Deane, C
Format: Journal article
Published: Frontiers Media 2019