Comparative analysis of the CDR loops of antigen receptors

Comparative analysis of the CDR loops of antigen receptors

The adaptive immune system uses two main types of antigen receptors: T-cell receptors (TCRs) and antibodies. While both proteins share a globally similar β-sandwich architecture, TCRs are specialised to recognise peptide antigens in the binding groove of the major histocompatibility complex, while a...

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Bibliographische Detailangaben
Hauptverfasser:	Wong, W, Leem, J, Deane, C
Format:	Journal article
Veröffentlicht:	Frontiers Media 2019

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