Comparative analysis of the CDR loops of antigen receptors
The adaptive immune system uses two main types of antigen receptors: T-cell receptors (TCRs) and antibodies. While both proteins share a globally similar β-sandwich architecture, TCRs are specialised to recognise peptide antigens in the binding groove of the major histocompatibility complex, while a...
| Hauptverfasser: | , , |
|---|---|
| Format: | Journal article |
| Veröffentlicht: |
Frontiers Media
2019
|