Regulation of MLL1 H3K4 methyltransferase activity by its core components.
Histone H3 Lys4 (H3K4) methylation is a prevalent mark associated with transcription activation. A common feature of several H3K4 methyltransferase complexes is the presence of three structural components (RbBP5, Ash2L and WDR5) and a catalytic subunit containing a SET domain. Here we report the fir...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2006
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