Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A.

Human adenovirus serotype 5 (AdH5) vector vaccines elicit strong immune responses to the encoded antigen and have been used in various disease models. We designed AdH5 vectors expressing antigen under the control of a human cytomegalovirus (HCMV) immediate-early promoter containing its intron A sequ...

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Bibliographic Details
Main Authors: Sridhar, S, Reyes-Sandoval, A, Draper, S, Moore, A, Gilbert, S, Gao, G, Wilson, J, Hill, A
Format: Journal article
Language:English
Published: 2008