A systematic review and empirical analysis of the relation between dose and duration of drug action
There is a log-linear relation between the dose and duration of action of drugs with single-compartment pharmacokinetics and direct, reversible mechanisms of action. However, it has been suggested that this relation does not extend to drugs whose metabolites are active or slowly eliminated, drugs wi...
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| Format: | Journal article |
| Language: | English |
| Published: |
Sage Publications
2010
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