Radiobiological determination of dose escalation and normal tissue toxicity in definitive chemoradiation therapy for esophageal cancer.

PURPOSE: This study investigated the trade-off in tumor coverage and organ-at-risk sparing when applying dose escalation for concurrent chemoradiation therapy (CRT) of mid-esophageal cancer, using radiobiological modeling to estimate local control and normal tissue toxicity. METHODS AND MATERIALS: T...

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Bibliographic Details
Main Authors: Warren, S, Partridge, M, Carrington, R, Hurt, C, Crosby, T, Hawkins, M
Format: Journal article
Language:English
Published: Elsevier 2014