Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.

Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill target cells for which they have no intrinsic specificity, a phenomenon we call effector cell retargeting (ECR). Thes...

詳細記述

書誌詳細
主要な著者: Gilliland, L, Clark, MR, Waldmann, H
フォーマット: Journal article
言語:English
出版事項: 1988