Secondary structure and assembly mechanism of an oligomeric channel protein.
The alpha-toxin of Staphylococcus aureus is secreted as a water-soluble, monomeric polypeptide (Mr 33 182) that can assemble into an oligomeric membrane channel. By chemical cross-linking, we have confirmed that the major form of the channel is a hexamer. The circular dichroism spectrum of this hexa...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1985
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