Refining molecular analysis in the pathways of colorectal carcinogenesis.
BACKGROUND and AIMS: In the stepwise model, specific genetic and epigenetic changes accumulate as colorectal adenomas progress to carcinomas (CRCs). CRCs also acquire global phenotypes, particularly microsatellite instability (MSI) and aneuploidy/polyploidy (chromosomal instability, CIN). Few chang...
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2005
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