Refining molecular analysis in the pathways of colorectal carcinogenesis.

Refining molecular analysis in the pathways of colorectal carcinogenesis.

BACKGROUND and AIMS: In the stepwise model, specific genetic and epigenetic changes accumulate as colorectal adenomas progress to carcinomas (CRCs). CRCs also acquire global phenotypes, particularly microsatellite instability (MSI) and aneuploidy/polyploidy (chromosomal instability, CIN). Few chang...

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Bibliographic Details
Main Authors:	Rowan, A, Halford, S, Gaasenbeek, M, Kemp, Z, Sieber, O, Volikos, E, Douglas, E, Fiegler, H, Carter, N, Talbot, I, Silver, A, Tomlinson, I
Format:	Journal article
Language:	English
Published:	2005

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