The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade

AIMS:ST-elevation myocardial infarction is associated with high levels of cardiac sympathetic drive and release of the co-transmitter neuropeptide Y (NPY). We hypothesized that despite beta-blockade, NPY promotes arrhythmogenesis via ventricular myocyte receptors. METHODS AND RESULTS:In 78 patients...

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Bibliographic Details
Main Authors: Kalla, M, Hao, G, Tapoulal, N, Tomek, J, Liu, K, Woodward, L, Oxford Acute Myocardial Infarction (Oxami) Study, Dall'Armellina, E, Banning, A, Choudhury, R, Neubauer, S, Kharbanda, R, Channon, K, Ajijola, O, Shivkumar, K, Paterson, D, Herring, N
Format: Journal article
Language:English
Published: Oxford University Press 2019