A nucleotide substitution model with nearest-neighbour interactions.
MOTIVATION: It is well known that neighbouring nucleotides in DNA sequences do not mutate independently of each other. In this paper, we introduce a context-dependent substitution model and derive an algorithm to calculate the likelihood of sequences evolving under this model. We use this algorithm...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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