A nucleotide substitution model with nearest-neighbour interactions.

MOTIVATION: It is well known that neighbouring nucleotides in DNA sequences do not mutate independently of each other. In this paper, we introduce a context-dependent substitution model and derive an algorithm to calculate the likelihood of sequences evolving under this model. We use this algorithm...

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Hlavní autoři: Lunter, G, Hein, J
Médium: Journal article
Jazyk:English
Vydáno: 2004