A nucleotide substitution model with nearest-neighbour interactions.

MOTIVATION: It is well known that neighbouring nucleotides in DNA sequences do not mutate independently of each other. In this paper, we introduce a context-dependent substitution model and derive an algorithm to calculate the likelihood of sequences evolving under this model. We use this algorithm...

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Main Authors: Lunter, G, Hein, J
格式: Journal article
语言:English
出版: 2004