Functional epistasis on a common MHC haplotype associated with multiple sclerosis.
Genes in the major histocompatibility complex (MHC) encode proteins important in activating antigen-specific immune responses. Alleles at adjacent MHC loci are often in strong linkage disequilibrium; however, little is known about the mechanisms responsible for this linkage disequilibrium. Here we r...
मुख्य लेखकों: | Gregersen, J, Kranc, K, Ke, X, Svendsen, P, Madsen, L, Thomsen, A, Cardon, L, Bell, J, Fugger, L |
---|---|
स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2006
|
समान संसाधन
-
Multiple sclerosis: MHC associations and therapeutic implications.
द्वारा: Holmes, S, और अन्य
प्रकाशित: (2005) -
Multiple Epistasis Interactions Within MHC Are Associated With Ulcerative Colitis
द्वारा: Jie Zhang, और अन्य
प्रकाशित: (2019-04-01) -
Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.
द्वारा: Dyment, D, और अन्य
प्रकाशित: (2005) -
Dissection of the multiple sclerosis associated DR2 haplotype.
द्वारा: Etzensperger, R, और अन्य
प्रकाशित: (2008) -
Epistasis: multiple sclerosis and the major histocompatibility complex.
द्वारा: Ramagopalan, S, और अन्य
प्रकाशित: (2009)