Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetes.

Arginase 1, via competing with nitric oxide (NO) synthase for the substrate L-arginine, may interfere with NO-mediated vascular responses. We tested the hypothesis that arginase 1 contributes to coronary vasomotor dysfunction in patients with diabetes mellitus (DM). Coronary arterioles were dissecte...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Beleznai, T, Feher, A, Spielvogel, D, Lansman, S, Bagi, Z
Format: Journal article
Sprache:English
Veröffentlicht: 2011