Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetes.

Arginase 1, via competing with nitric oxide (NO) synthase for the substrate L-arginine, may interfere with NO-mediated vascular responses. We tested the hypothesis that arginase 1 contributes to coronary vasomotor dysfunction in patients with diabetes mellitus (DM). Coronary arterioles were dissecte...

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Détails bibliographiques
Auteurs principaux: Beleznai, T, Feher, A, Spielvogel, D, Lansman, S, Bagi, Z
Format: Journal article
Langue:English
Publié: 2011