The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone.

Estrogen withdrawal in women leads initially to rapid bone loss caused by increased numbers or activity of osteoclasts. We previously have noted apoptosis of lacunar osteocytes associated with conditions of high bone turnover. Therefore, in this study, we investigated whether the increased bone loss...

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Detalhes bibliográficos
Main Authors: Tomkinson, A, Reeve, J, Shaw, R, Noble, B
Formato: Journal article
Idioma:English
Publicado em: 1997