Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests CCR1 as a therapeutic target

<p>Metastatic tumour progression is facilitated by tumour associated macrophages (TAMs) that enforce pro-tumour mechanisms and suppress immunity. In pulmonary metastases, it is unclear whether TAMs comprise tissue resident or infiltrating, recruited macrophages; and the different expression pa...

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Bibliographic Details
Main Authors: Tapmeier, TT, Howell, JH, Zhao, L, Papiez, BW, Schnabel, JA, Muschel, RJ, Gal, A
Format: Journal article
Language:English
Published: Springer Nature 2022