Neuronal enhancers are hotspots for DNA single-strand break repair

Defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons1,2. The cellular genome is subjected to a constant barrage of endogenous DNA damage, but surprisingly little is known ab...

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Bibliographic Details
Main Authors:	Wu, W, Hill, SE, Nathan, WJ, Paiano, J, Callen, E, Wang, D, Shinoda, K, van Wietmarschen, N, Colón-Mercado, JM, Zong, D, De Pace, R, Shih, H-Y, Coon, S, Parsadanian, M, Pavani, R, Hanzlikova, H, Park, S, Jung, SK, McHugh, PJ, Canela, A, Chen, C, Casellas, R, Caldecott, KW, Ward, ME, Nussenzweig, A
Format:	Journal article
Language:	English
Published:	Nature 2021

Neuronal enhancers are hotspots for DNA single-strand break repair

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