CBP/p300 bromodomains regulate amyloid-like protein aggregation upon aberrant lysine acetylation

Lysine acetylation is becoming increasingly recognized as a general biological principle in cellular homeostasis, and is subject to abnormal control in different human pathologies. Here, we describe a global effect on amyloid-like protein aggregation in human cells that results from aberrant lysine...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Olzscha, H, Fedorov, O, Kessler, B, Knapp, S, La Thangue, N
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Cell Press 2016