Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues
Voltage-dependent K⁺ channels transfer the voltage sensor movement into gate opening or closure through an electromechanical coupling. To test functionally whether an interaction between the S4-S5 linker (L45) and the cytoplasmic end of S6 (S6<sub>T</sub>) constitutes this coupling, the...
Auteurs principaux: | , , , , , |
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Format: | Journal article |
Langue: | English |
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Rockefeller University Press
2008
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