Modifying the maternal microbiota alters the gut-brain metabolome and prevents emotional dysfunction in the adult offspring of obese dams

Maternal obesity disturbs brain-gut-microbiota interactions and induces negative affect in the offspring, but its impact on gut and brain metabolism in the offspring (F1) are unknown. Here, we tested whether perinatal intake of a multispecies probiotic could mitigate the abnormal emotional behavior...

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Bibliographic Details
Main Authors: Radford-Smith, DE, Probert, F, Burnet, PWJ, Anthony, DC
Format: Journal article
Language:English
Published: National Academy of Sciences 2022