Death commitment point is advanced by axotomy in sympathetic neurons.

Axotomized neurons have several characteristics that are different from intact neurons. Here we show that, unlike established cultures, the axotomized sympathetic neurons deprived of NGF become committed to die before caspase activation, since the same proportion of NGF-deprived neurons are rescued...

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Bibliographic Details
Main Authors: Fletcher, G, Xue, L, Passingham, S, Tolkovsky, A
Format: Journal article
Language:English
Published: 2000