Estimating individual exposure to malaria using local prevalence of malaria infection in the field.

BACKGROUND: Heterogeneity in malaria exposure complicates survival analyses of vaccine efficacy trials and confounds the association between immune correlates of protection and malaria infection in longitudinal studies. Analysis may be facilitated by taking into account the variability in individual...

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Bibliographic Details
Main Authors: Olotu, A, Fegan, G, Wambua, J, Nyangweso, G, Ogada, E, Drakeley, C, Marsh, K, Bejon, P
Format: Journal article
Language:English
Published: Public Library of Science 2012