Antitumor and antiangiogenic activity of cediranib in a preclinical model of renal cell carcinoma.

Cediranib is a highly potent and selective vascular endothelial growth factor (VEGF) signaling inhibitor with activity against all three VEGF receptors (VEGFRs) that inhibits angiogenesis and growth of human tumor xenografts in vivo. The present study evaluated the antitumor and antiangiogenic activ...

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Bibliographic Details
Main Authors: Medinger, M, Esser, N, Zirrgiebel, U, Ryan, A, Jürgensmeier, J, Drevs, J
Format: Journal article
Language:English
Published: 2009