Conformational changes and gating at the selectivity filter of potassium channels.

The translocation of ions and water across cell membranes is a prerequisite for many of life's processes. K(+) channels are a diverse family of integral membrane proteins through which K(+) can pass selectively. There is an ongoing debate about the nature of conformational changes associated wi...

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Bibliographic Details
Main Authors: Domene, C, Klein, M, Branduardi, D, Gervasio, F, Parrinello, M
Format: Journal article
Language:English
Published: 2008