Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies

Current screening methods for ovarian cancer can only detect advanced disease. Earlier detection has proved difficult because the molecular precursors involved in the natural history of the disease are unknown. To identify early driver mutations in ovarian cancer cells, we used dense whole genome se...

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Bibliographic Details
Main Authors:	Hellner, K, Miranda, F, Fotso Chedom, D, Herrero-Gonzalez, S, Hayden, D, Tearle, R, Artibani, M, KaramiNejadRanjbar, M, Williams, R, Gaitskell, K, Elorbany, S, Xu, R, Laios, A, Buiga, P, Ahmed, K, Dhar, S, Zhang, R, Campo, L, Myers, K, Lozano, M, Ruiz-Miró, M, Gatius, S, Mota, A, Moreno-Bueno, G, Matias-Guiu, X, Benítez, J, Witty, L, McVean, G, Leedham, S, Tomlinson, I, Drmanac, R, Cazier, J, Klein, R, Dunne, K, Bast, R, Kennedy, S, Hassan, B, Lise, S, Garcia, M, Peters, B, Yau, C, Sauka-Spengler, T, Ahmed, A
Format:	Journal article
Language:	English
Published:	Elsevier 2016

Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies

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