The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.

Previous work has shown an association between the K variant of the butyrylcholinesterase (BCHE) gene and Alzheimer's disease (AD) in patients carrying the epsilon4 allele of ApoE. We attempted to replicate this finding in 181 UK white AD cases and 71 controls. No difference was found in BCHE-K...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Kehoe, P, Williams, H, Holmans, P, Wilcock, G, Cairns, N, Neal, J, Owen, M
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	1998

Gelijkaardige items

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
door: Kehoe, P, et al.
Gepubliceerd in: (1999)

Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.
door: Kehoe, P, et al.
Gepubliceerd in: (1996)

Onset of Alzheimer disease in apolipoprotein ɛ4 carriers is earlier in butyrylcholinesterase K variant carriers
door: Roger M. Lane, et al.
Gepubliceerd in: (2024-04-01)

Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group.
door: Kehoe, P, et al.
Gepubliceerd in: (1996)

Association of butyrylcholinesterase K variant with cholinesterase-positive neuritic plaques in the temporal cortex in late-onset Alzheimer's disease.
door: Lehmann, D, et al.
Gepubliceerd in: (2000)

Presenilin-1 polymorphism and Alzheimer's disease [6]
door: Kehoe, P, et al.
Gepubliceerd in: (1996)

Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation.
door: Holmes, C, et al.
Gepubliceerd in: (2005)

Common variants of ACE contribute to variable age-at-onset of Alzheimer's disease.
door: Kehoe, P, et al.
Gepubliceerd in: (2004)

ApoE epsilon 2 and butyrylcholinesterase K variant are associated with coronary heart disease in type 2 diabetes
door: Horton, V, et al.
Gepubliceerd in: (2000)

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.
door: Blomqvist, M, et al.
Gepubliceerd in: (2005)

Butyrylcholinesterase K variant is associated with type 2 diabetes in UK Caucasians
door: Hashim, Y, et al.
Gepubliceerd in: (2000)

Association between butyrylcholinesterase K variant and mild cognitive impairment in the Thai community-dwelling patients
door: Pongthanaracht N, et al.
Gepubliceerd in: (2017-05-01)

Flavonoids as Inhibitors of Human Butyrylcholinesterase Variants
door: Maja Katalinić, et al.
Gepubliceerd in: (2014-01-01)

Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
door: Kehoe, P, et al.
Gepubliceerd in: (2007)

Butyrylcholinesterase K variant associated with higher enzyme activity in the temporal cortex of elderly patients.
door: Tasker, A, et al.
Gepubliceerd in: (2008)

Common variants of ACE contribute to variable age at onset of Alzheimer's disease
door: Katzov, H, et al.
Gepubliceerd in: (2004)

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.
door: Katzov, H, et al.
Gepubliceerd in: (2004)

The renin angiotensin system in Alzheimer's disease - Do updates high-light a clinical and biological dichotomy?
door: Kehoe, P, et al.
Gepubliceerd in: (2006)

Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes
door: Vitor G.L. Dantas, et al.
Gepubliceerd in: (2011-01-01)

Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer’s disease treatment
door: Sani Muhammad Uzairu, et al.
Gepubliceerd in: (2022-09-01)

Butyrylcholinesterase K variant on chromosome 3 q is associated with Type II diabetes in white Caucasian subjects.
door: Hashim, Y, et al.
Gepubliceerd in: (2001)

Tumour necrosis factor-alpha gene polymorphisms and Alzheimer's disease.
door: Culpan, D, et al.
Gepubliceerd in: (2003)

Benzene-1,3-diol derivatives as the inhibitors of butyrylcholinesterase: An emergent target of Alzheimer’s disease
door: Dongliang Yin, et al.
Gepubliceerd in: (2022-01-01)

Aaptamine – a dual acetyl – and butyrylcholinesterase inhibitor as potential anti-Alzheimer’s disease agent
door: Shuang Miao, et al.
Gepubliceerd in: (2022-12-01)

Butyrylcholinesterase Protein Ends in the Pathogenesis of Alzheimer’s Disease—Could <i>BCHE</i> Genotyping Be Helpful in Alzheimer’s Therapy?
door: Jacek Jasiecki, et al.
Gepubliceerd in: (2019-10-01)

TNFR-associated factor-2 (TRAF-2) expression in Alzheimer's disease
door: Culpan, D, et al.
Gepubliceerd in: (2004)

The relationship between CAV-1 and cerebral amyloid angiopathy in Alzheimer's disease
door: Chalmers, K, et al.
Gepubliceerd in: (2004)

Widely Spread Butyrylcholinesterase Can Hydrolyze Acetylcholine in the Normal and Alzheimer Brain
door: Marsel Mesulam, et al.
Gepubliceerd in: (2002-02-01)

Haplotypes extending across ACE are associated with Alzheimer's disease.
door: Kehoe, P, et al.
Gepubliceerd in: (2003)

Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease
door: Chuanyu Yu, et al.
Gepubliceerd in: (2024-12-01)

Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease
door: Ana Matošević, et al.
Gepubliceerd in: (2022-09-01)

Investigation of Association between Susceptibility to Leprosy and SNPs inside and near the BCHE Gene of Butyrylcholinesterase
door: Henrique J. P. Gomes, et al.
Gepubliceerd in: (2012-01-01)

The ACE gene and Alzheimer's disease susceptibility.
door: Narain, Y, et al.
Gepubliceerd in: (2000)

Biophenols of mints: Antioxidant, acetylcholinesterase, butyrylcholinesterase and histone deacetylase inhibition activities targeting Alzheimer’s disease treatment
door: Doaa M. Hanafy, et al.
Gepubliceerd in: (2017-06-01)

Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl–Pyridazine Moiety for the Potential Treatment of Alzheimer’s Disease
door: Mohamed Elsawalhy, et al.
Gepubliceerd in: (2024-10-01)

Correction: Evolution of Acetylcholinesterase and Butyrylcholinesterase in the Vertebrates: An Atypical Butyrylcholinesterase from the Medaka.
door: Leo Pezzementi, et al.
Gepubliceerd in: (2011-01-01)

Treating Alzheimer's disease.
door: Wilcock, G, et al.
Gepubliceerd in: (1995)

Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates: an atypical butyrylcholinesterase from the Medaka Oryzias latipes.
door: Leo Pezzementi, et al.
Gepubliceerd in: (2011-02-01)

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.
door: Miners, J, et al.
Gepubliceerd in: (2006)

Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease.
door: Culpan, D, et al.
Gepubliceerd in: (2007)