Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub.

Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub.

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Repulsive guidance molecule family members (RGMs) control fundamental and diverse cellular processes, including motility and adhesion, immune cell regulation, and systemic iron metabolism. However, it is not known how RGMs initiate signaling through their common cell-surface receptor, neogenin (NEO1...

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Detalles Bibliográficos
Autores principales: Bell, C, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R, Aricescu, A, Pasterkamp, R, Siebold, C
Formato: Journal article
Lenguaje:English
Publicado: 2013

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