Leukocyte adhesion deficiency II: therapy and genetic defect.

Leukocyte adhesion deficiency II (LAD II) is a rare congenital disease which is caused by a defect in fucosylation of glycoconjugates. Hypofucosylated structures include ligands for the selectin family of adhesion molecules. This results in a leukocyte adhesion defect causing an immunodeficiency. In...

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Detalles Bibliográficos
Autores principales: Wild, M, Lühn, K, Marquardt, T, Vestweber, D
Formato: Journal article
Lenguaje:English
Publicado: 2002