Leukocyte adhesion deficiency II: therapy and genetic defect.

Leukocyte adhesion deficiency II (LAD II) is a rare congenital disease which is caused by a defect in fucosylation of glycoconjugates. Hypofucosylated structures include ligands for the selectin family of adhesion molecules. This results in a leukocyte adhesion defect causing an immunodeficiency. In...

Полное описание

Библиографические подробности
Главные авторы: Wild, M, Lühn, K, Marquardt, T, Vestweber, D
Формат: Journal article
Язык:English
Опубликовано: 2002