Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?

Using positron emission tomography and the selective 5-HT1A receptor radioligand [11C]WAY100635, we previously demonstrated a preferential occupancy of 5-HT1A autoreceptors, compared to postsynaptic receptors by pindolol in healthy volunteers. We have speculated that preferential occupancy may be cl...

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Bibliographic Details
Main Authors: Rabiner, E, Bhagwagar, Z, Gunn, R, Cowen, P, Grasby, P
Format: Journal article
Language:English
Published: 2004