Glucose metabolism and oxygen availability govern reactivation from latency of the human retrovirus HTLV-1
The human retrovirus HTLV-1 causes a haematological malignancy or neuroinflammatory disease in ~10% of infected individuals. HTLV-1 primarily infects CD4+ T-lymphocytes and persists as a provirus integrated in their genome. HTLV-1 appears transcriptionally latent in freshly-isolated cells; however,...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
Cell Press
2017
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