A complex barcode underlies the heterogeneous response of p53 to stress.

The tumour suppressor p53 is activated following stress and initiates a heterogeneous response in a cell-, tissue- and stress-dependent manner. This heterogeneity is reflected in the different physiological outcomes that follow p53 activation. One mechanism that may contribute to this variability is...

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Bibliographic Details
Main Authors: Murray-Zmijewski, F, Slee, E, Lu, X
Format: Journal article
Language:English
Published: 2008