Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
Pso2/Snm1 plays a key role in the repair of DNA interstrand cross-links in yeast. Human cells possess three orthologues of Pso2; SNM1A, SNM1B/Apollo and SNM1C/Artemis. Studies using mammalian cells disrupted or depleted for these genes have yielded equivocal evidence that any of these is a true func...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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