Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.

Pso2/Snm1 plays a key role in the repair of DNA interstrand cross-links in yeast. Human cells possess three orthologues of Pso2; SNM1A, SNM1B/Apollo and SNM1C/Artemis. Studies using mammalian cells disrupted or depleted for these genes have yielded equivocal evidence that any of these is a true func...

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Bibliographic Details
Main Authors: Hazrati, A, Ramis-Castelltort, M, Sarkar, S, Barber, L, Schofield, C, Hartley, J, McHugh, P
Format: Journal article
Language:English
Published: 2008