Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters

In the mid-1990s, whole-cell (wP) pertussis vaccines were associated with local and systemic adverse events, which prompted their replacement with acellular (aP) vaccines in many high-income countries. In the past decade rates of pertussis disease have increased in children receiving only acellular...

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Bibliographic Details
Main Authors: da Silva Antunes, R, Babor, M, Carpenter, C, Khalil, N, Cortese, M, Mentzer, A, Seumois, G, Petro, C, Purcell, L, Vijayanand, P, Crotty, S, Pulendran, B, Peters, B, Sette, A
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2018