Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters
In the mid-1990s, whole-cell (wP) pertussis vaccines were associated with local and systemic adverse events, which prompted their replacement with acellular (aP) vaccines in many high-income countries. In the past decade rates of pertussis disease have increased in children receiving only acellular...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Clinical Investigation
2018
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